BDBM50097995 5-Phenyl-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::CHEMBL168829

SMILES: Nc1ncnc2n(cc(-c3ccccc3)c12)C1CCNC1

InChI Key: InChIKey=XNIBNLVJQPSPNT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50097995 (5-Phenyl-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyrimi...) Show SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)C1CCNC1 Show InChI InChI=1S/C16H17N5/c17-15-14-13(11-4-2-1-3-5-11)9-21(12-6-7-18-8-12)16(14)20-10-19-15/h1-5,9-10,12,18H,6-8H2,(H2,17,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Research Curated by ChEMBL					Assay Description Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mL				Bioorg Med Chem Lett 11: 853-6 (2001) BindingDB Entry DOI: 10.7270/Q29P30XJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50097995 (5-Phenyl-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyrimi...) Show SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)C1CCNC1 Show InChI InChI=1S/C16H17N5/c17-15-14-13(11-4-2-1-3-5-11)9-21(12-6-7-18-8-12)16(14)20-10-19-15/h1-5,9-10,12,18H,6-8H2,(H2,17,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Research Curated by ChEMBL					Assay Description Concentration required for inhibition of epidermal growth factor receptor (EGF-R) by tyrosine kinase enzyme activity				Bioorg Med Chem Lett 11: 853-6 (2001) BindingDB Entry DOI: 10.7270/Q29P30XJ
					More data for this Ligand-Target Pair