BDBM50098130 5-Methylsulfanyl-4-[2-(2-piperidin-1-yl-ethylamino)-thiazol-4-yl]-thiophene-2-carboxamidine::CHEMBL173483

SMILES: CSc1sc(cc1-c1csc(NCCN2CCCCC2)n1)C(N)=N

InChI Key: InChIKey=MRQHVGIOSIAEKH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50098130 (5-Methylsulfanyl-4-[2-(2-piperidin-1-yl-ethylamino...) Show SMILES CSc1sc(cc1-c1csc(NCCN2CCCCC2)n1)C(N)=N Show InChI InChI=1S/C16H23N5S3/c1-22-15-11(9-13(24-15)14(17)18)12-10-23-16(20-12)19-5-8-21-6-3-2-4-7-21/h9-10H,2-8H2,1H3,(H3,17,18)(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)				Bioorg Med Chem Lett 11: 915-8 (2001) BindingDB Entry DOI: 10.7270/Q2J67G5B
					More data for this Ligand-Target Pair