BDBM50098138 4-[2-(2-Bromo-4-methyl-phenylamino)-thiazol-4-yl]-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL171642

SMILES: CSc1sc(cc1-c1csc(Nc2ccc(C)cc2Br)n1)C(N)=N

InChI Key: InChIKey=BBZQWPQSGQXDJT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50098138 (4-[2-(2-Bromo-4-methyl-phenylamino)-thiazol-4-yl]-...) Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(C)cc2Br)n1)C(N)=N Show InChI InChI=1S/C16H15BrN4S3/c1-8-3-4-11(10(17)5-8)20-16-21-12(7-23-16)9-6-13(14(18)19)24-15(9)22-2/h3-7H,1-2H3,(H3,18,19)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)				Bioorg Med Chem Lett 11: 915-8 (2001) BindingDB Entry DOI: 10.7270/Q2J67G5B
					More data for this Ligand-Target Pair