BDBM50098146 4-[2-(Benzhydryl-amino)-thiazol-4-yl]-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL170477

SMILES: CSc1sc(cc1-c1csc(NC(c2ccccc2)c2ccccc2)n1)C(N)=N

InChI Key: InChIKey=ABEISAYFSWNEFB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50098146 (4-[2-(Benzhydryl-amino)-thiazol-4-yl]-5-methylsulf...) Show SMILES CSc1sc(cc1-c1csc(NC(c2ccccc2)c2ccccc2)n1)C(N)=N Show InChI InChI=1S/C22H20N4S3/c1-27-21-16(12-18(29-21)20(23)24)17-13-28-22(25-17)26-19(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-13,19H,1H3,(H3,23,24)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)				Bioorg Med Chem Lett 11: 915-8 (2001) BindingDB Entry DOI: 10.7270/Q2J67G5B
					More data for this Ligand-Target Pair