BDBM50098155 4-[2-(4-Methyl-benzylamino)-thiazol-4-yl]-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL173392

SMILES: CSc1sc(cc1-c1csc(NCc2ccc(C)cc2)n1)C(N)=N

InChI Key: InChIKey=YODCXSDDGBHEEN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50098155 (4-[2-(4-Methyl-benzylamino)-thiazol-4-yl]-5-methyl...) Show SMILES CSc1sc(cc1-c1csc(NCc2ccc(C)cc2)n1)C(N)=N Show InChI InChI=1S/C17H18N4S3/c1-10-3-5-11(6-4-10)8-20-17-21-13(9-23-17)12-7-14(15(18)19)24-16(12)22-2/h3-7,9H,8H2,1-2H3,(H3,18,19)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)				Bioorg Med Chem Lett 11: 915-8 (2001) BindingDB Entry DOI: 10.7270/Q2J67G5B
					More data for this Ligand-Target Pair