null

SMILES: CS(=O)(=O)N1CCC[C@H](C1)n1c2c(cnc3[nH]ccc23)[nH]c1=O

InChI Key: InChIKey=UBXFCEXXJLXQHL-SECBINFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50098430 (CHEMBL3593588) Show SMILES CS(=O)(=O)N1CCC[C@H](C1)n1c2c(cnc3[nH]ccc23)[nH]c1=O |r| Show InChI InChI=1S/C14H15N5O3S/c1-23(21,22)18-6-2-3-9(8-18)19-12-10-4-5-15-13(10)16-7-11(12)17-14(19)20/h4-5,7,9H,2-3,6,8H2,1H3/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate and ATP incubated for 1 hr by ELISA method				Bioorg Med Chem 23: 4846-59 (2015) Article DOI: 10.1016/j.bmc.2015.05.028 BindingDB Entry DOI: 10.7270/Q2SX6G04
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50098430 (CHEMBL3593588) Show SMILES CS(=O)(=O)N1CCC[C@H](C1)n1c2c(cnc3[nH]ccc23)[nH]c1=O |r| Show InChI InChI=1S/C14H15N5O3S/c1-23(21,22)18-6-2-3-9(8-18)19-12-10-4-5-15-13(10)16-7-11(12)17-14(19)20/h4-5,7,9H,2-3,6,8H2,1H3/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate and ATP incubated for 1 hr by ELISA method				Bioorg Med Chem 23: 4846-59 (2015) Article DOI: 10.1016/j.bmc.2015.05.028 BindingDB Entry DOI: 10.7270/Q2SX6G04
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50098430 (CHEMBL3593588) Show SMILES CS(=O)(=O)N1CCC[C@H](C1)n1c2c(cnc3[nH]ccc23)[nH]c1=O |r| Show InChI InChI=1S/C14H15N5O3S/c1-23(21,22)18-6-2-3-9(8-18)19-12-10-4-5-15-13(10)16-7-11(12)17-14(19)20/h4-5,7,9H,2-3,6,8H2,1H3/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate and ATP incubated for 1 hr by ELISA method				Bioorg Med Chem 23: 4846-59 (2015) Article DOI: 10.1016/j.bmc.2015.05.028 BindingDB Entry DOI: 10.7270/Q2SX6G04
					More data for this Ligand-Target Pair