BDBM50098456 4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(3-methoxy-phenyl)-amino]-N,N-diethyl-benzamide::CHEMBL175342
SMILES: CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@H]1C)c1cccc(OC)c1
InChI Key: InChIKey=KEHOXWIRLSRNHN-JIPXPUAJSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50098456 (4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain | J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50098456 (4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >6.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Affinity of [3H]DAMGO to the mu opioid receptor from rat brain | J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50098456 (4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >7.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain | J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G | |||||||||||
More data for this Ligand-Target Pair |