BDBM50098546 (R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL283065
SMILES: COc1cccc(OC)c1-c1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12
InChI Key: InChIKey=CCSCYJFJDDPPKK-HXUWFJFHSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serotonin (5-HT) receptor (Rattus norvegicus (rat)) | BDBM50098546![]() ((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from rat 5-hydroxytryptamine 7 receptor expressed in CHO cells | J Med Chem 44: 1337-40 (2001) BindingDB Entry DOI: 10.7270/Q23X85WM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Rattus norvegicus (rat)) | BDBM50098546![]() ((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense Curated by ChEMBL | Assay Description Binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor was determined using [3H]5-HT as radioligand | J Med Chem 46: 5638-50 (2003) Article DOI: 10.1021/jm030841r BindingDB Entry DOI: 10.7270/Q29W0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50098546![]() ((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 554 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human 5-hydroxytryptamine 1A receptor expressed in CHO cells | J Med Chem 44: 1337-40 (2001) BindingDB Entry DOI: 10.7270/Q23X85WM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50098546![]() ((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [3H]-Raclopride from human dopamine receptor D2A expressed in mouse Ltk cells | J Med Chem 44: 1337-40 (2001) BindingDB Entry DOI: 10.7270/Q23X85WM | |||||||||||
More data for this Ligand-Target Pair |