BDBM50098721 CHEMBL3593327

SMILES: Cc1cccc(N\N=C(/C#N)C(=O)c2cc(on2)C(C)(C)C)c1

InChI Key: InChIKey=HUUSEJULQRAJKT-XSFVSMFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 4 (Mus musculus)	BDBM50098721 (CHEMBL3593327) Show SMILES Cc1cccc(N\N=C(/C#N)C(=O)c2cc(on2)C(C)(C)C)c1 Show InChI InChI=1S/C17H18N4O2/c1-11-6-5-7-12(8-11)19-20-14(10-18)16(22)13-9-15(23-21-13)17(2,3)4/h5-9,19H,1-4H3/b20-14+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assay				J Med Chem 58: 6033-47 (2015) Article DOI: 10.1021/acs.jmedchem.5b00635 BindingDB Entry DOI: 10.7270/Q29025JD
					More data for this Ligand-Target Pair