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BDBM50098789 CHEMBL3593465

SMILES: Clc1cccc(N\N=C(/C#N)C(=O)c2cc(on2)C2CCCCC2)c1

InChI Key: InChIKey=XXHQSAJDZVSBSE-CJLVFECKSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098789   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rap guanine nucleotide exchange factor 4


(Mus musculus)		BDBM50098789
PNG
(CHEMBL3593465)
Show SMILES Clc1cccc(N\N=C(/C#N)C(=O)c2cc(on2)C2CCCCC2)c1
Show InChI InChI=1S/C18H17ClN4O2/c19-13-7-4-8-14(9-13)21-22-16(11-20)18(24)15-10-17(25-23-15)12-5-2-1-3-6-12/h4,7-10,12,21H,1-3,5-6H2/b22-16+
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 1.13E+4n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assay

J Med Chem 58: 6033-47 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00635
BindingDB Entry DOI: 10.7270/Q29025JD
More data for this
Ligand-Target Pair