BDBM50099234 1-[3-(5-Isopropenyl-6-methoxy-naphthalen-2-yl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl]-propan-1-one::CHEMBL39764

SMILES: CCC(=O)C1C2CCC(CC1c1ccc3c(C(C)=C)c(OC)ccc3c1)N2C

InChI Key: InChIKey=HNDBRFIOUNWISY-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50099234 (1-[3-(5-Isopropenyl-6-methoxy-naphthalen-2-yl)-8-m...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3c(C(C)=C)c(OC)ccc3c1)N2C |TLB:27:26:4.10.9:6.7,THB:11:10:26:6.7,2:4:26:6.7| Show InChI InChI=1S/C25H31NO2/c1-6-22(27)25-20(14-18-9-11-21(25)26(18)4)17-7-10-19-16(13-17)8-12-23(28-5)24(19)15(2)3/h7-8,10,12-13,18,20-21,25H,2,6,9,11,14H2,1,3-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50099234 (1-[3-(5-Isopropenyl-6-methoxy-naphthalen-2-yl)-8-m...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3c(C(C)=C)c(OC)ccc3c1)N2C |TLB:27:26:4.10.9:6.7,THB:11:10:26:6.7,2:4:26:6.7| Show InChI InChI=1S/C25H31NO2/c1-6-22(27)25-20(14-18-9-11-21(25)26(18)4)17-7-10-19-16(13-17)8-12-23(28-5)24(19)15(2)3/h7-8,10,12-13,18,20-21,25H,2,6,9,11,14H2,1,3-5H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Affinity for the displacement of [3H]-paroxetine binding to norepinephrine transporter (NET) in rat frontal cortex membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099234 (1-[3-(5-Isopropenyl-6-methoxy-naphthalen-2-yl)-8-m...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3c(C(C)=C)c(OC)ccc3c1)N2C |TLB:27:26:4.10.9:6.7,THB:11:10:26:6.7,2:4:26:6.7| Show InChI InChI=1S/C25H31NO2/c1-6-22(27)25-20(14-18-9-11-21(25)26(18)4)17-7-10-19-16(13-17)8-12-23(28-5)24(19)15(2)3/h7-8,10,12-13,18,20-21,25H,2,6,9,11,14H2,1,3-5H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair