BDBM50099286 4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid methylamide::CHEMBL289914

SMILES: CNC(=O)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1

InChI Key: InChIKey=ABJWYMYTLWBPQC-OLZOCXBDSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50099286 (4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...) Show SMILES CNC(=O)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI InChI=1S/C14H19ClN2O/c1-16-14(18)13-9-17(2)8-7-12(13)10-3-5-11(15)6-4-10/h3-6,12-13H,7-9H2,1-2H3,(H,16,18)/t12-,13+/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to inhibit high affinity uptake of norepinephrine transporter into the nerve endings of rat synaptosomes using [3H]NE as a radioligand				J Med Chem 44: 1615-22 (2001) BindingDB Entry DOI: 10.7270/Q2513ZXB
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099286 (4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...) Show SMILES CNC(=O)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI InChI=1S/C14H19ClN2O/c1-16-14(18)13-9-17(2)8-7-12(13)10-3-5-11(15)6-4-10/h3-6,12-13H,7-9H2,1-2H3,(H,16,18)/t12-,13+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high affinity DA uptake into rat synaptosomes using [3H]DA				J Med Chem 44: 1615-22 (2001) BindingDB Entry DOI: 10.7270/Q2513ZXB
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099286 (4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...) Show SMILES CNC(=O)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI InChI=1S/C14H19ClN2O/c1-16-14(18)13-9-17(2)8-7-12(13)10-3-5-11(15)6-4-10/h3-6,12-13H,7-9H2,1-2H3,(H,16,18)/t12-,13+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Displacement of [3H]mazindol binding to dopamine transporter (DAT) in rat synaptosomes				J Med Chem 44: 1615-22 (2001) BindingDB Entry DOI: 10.7270/Q2513ZXB
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50099286 (4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...) Show SMILES CNC(=O)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI InChI=1S/C14H19ClN2O/c1-16-14(18)13-9-17(2)8-7-12(13)10-3-5-11(15)6-4-10/h3-6,12-13H,7-9H2,1-2H3,(H,16,18)/t12-,13+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high affinity serotonin uptake into rat synaptosomes using [3H]5-HT				J Med Chem 44: 1615-22 (2001) BindingDB Entry DOI: 10.7270/Q2513ZXB
					More data for this Ligand-Target Pair