null
SMILES: CN1C[C@H]([C@@H](C1)c1ccc(F)cc1)C(=O)c1ccc(F)cc1
InChI Key: InChIKey=BRTUVYIEVZPBTD-DLBZAZTESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50099307 ((4-Fluoro-phenyl)-[(3S,4R)-4-(4-fluoro-phenyl)-1-m...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of [3H]5-HT uptake at Serotonin transporter in rat mid brain | Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50099307 ((4-Fluoro-phenyl)-[(3S,4R)-4-(4-fluoro-phenyl)-1-m...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of [3H]NE uptake at Norepinephrine transporter in rat parietal/occipital cortex was determined | Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50099307 ((4-Fluoro-phenyl)-[(3S,4R)-4-(4-fluoro-phenyl)-1-m...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex. | Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F | |||||||||||
More data for this Ligand-Target Pair |