BDBM50101103 8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-carboxylic acid methyl ester::CHEMBL46196

SMILES: COC(=O)c1ccc2c(c1)[nH]c(=O)c1cc(F)ccc21

InChI Key: InChIKey=GYVJOGVOINMSIW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50101103 (8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-carbox...) Show SMILES COC(=O)c1ccc2c(c1)[nH]c(=O)c1cc(F)ccc21 Show InChI InChI=1S/C15H10FNO3/c1-20-15(19)8-2-4-11-10-5-3-9(16)7-12(10)14(18)17-13(11)6-8/h2-7H,1H3,(H,17,18)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 11: 1687-90 (2001) BindingDB Entry DOI: 10.7270/Q2348KWN
					More data for this Ligand-Target Pair