BDBM50101110 2-Amino-10-methyl-3-trifluoromethyl-5H-phenanthridin-6-one::CHEMBL45707

SMILES: Cc1cccc2c1c1cc(N)c(cc1[nH]c2=O)C(F)(F)F

InChI Key: InChIKey=YLLSINQKXQIDCU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50101110 (2-Amino-10-methyl-3-trifluoromethyl-5H-phenanthrid...) Show SMILES Cc1cccc2c1c1cc(N)c(cc1[nH]c2=O)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O/c1-7-3-2-4-8-13(7)9-5-11(19)10(15(16,17)18)6-12(9)20-14(8)21/h2-6H,19H2,1H3,(H,20,21)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)				Bioorg Med Chem Lett 11: 1687-90 (2001) BindingDB Entry DOI: 10.7270/Q2348KWN
					More data for this Ligand-Target Pair