null

SMILES: Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCOCC1

InChI Key: InChIKey=PUSXOKJZGMZXRI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50101207 (2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-bu...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCOCC1 Show InChI InChI=1S/C35H44N4O2/c1-25-21-26(2)23-28(22-25)33-30(12-16-36-13-6-5-7-27-10-14-37-15-11-27)31-24-29(8-9-32(31)38-33)35(3,4)34(40)39-17-19-41-20-18-39/h8-11,14-15,21-24,36,38H,5-7,12-13,16-20H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50101207 (2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-bu...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCOCC1 Show InChI InChI=1S/C35H44N4O2/c1-25-21-26(2)23-28(22-25)33-30(12-16-36-13-6-5-7-27-10-14-37-15-11-27)31-24-29(8-9-32(31)38-33)35(3,4)34(40)39-17-19-41-20-18-39/h8-11,14-15,21-24,36,38H,5-7,12-13,16-20H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50101207 (2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-bu...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCOCC1 Show InChI InChI=1S/C35H44N4O2/c1-25-21-26(2)23-28(22-25)33-30(12-16-36-13-6-5-7-27-10-14-37-15-11-27)31-24-29(8-9-32(31)38-33)35(3,4)34(40)39-17-19-41-20-18-39/h8-11,14-15,21-24,36,38H,5-7,12-13,16-20H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GnRH-stimulated phosphatidyinositol (PI) hydrolysis in cloned chinese hamster ovary (CHO) cells expressing human GnRH receptor.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair