BDBM50101239 2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-1-pyrrolidin-1-yl-propan-1-one::CHEMBL300095

SMILES: Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCCC1

InChI Key: InChIKey=HNKINIUXSPUALZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50101239   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50101239 (2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-bu...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCCC1 Show InChI InChI=1S/C35H44N4O/c1-25-21-26(2)23-28(22-25)33-30(14-18-36-15-6-5-9-27-12-16-37-17-13-27)31-24-29(10-11-32(31)38-33)35(3,4)34(40)39-19-7-8-20-39/h10-13,16-17,21-24,36,38H,5-9,14-15,18-20H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50101239 (2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-bu...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCCC1 Show InChI InChI=1S/C35H44N4O/c1-25-21-26(2)23-28(22-25)33-30(14-18-36-15-6-5-9-27-12-16-37-17-13-27)31-24-29(10-11-32(31)38-33)35(3,4)34(40)39-19-7-8-20-39/h10-13,16-17,21-24,36,38H,5-9,14-15,18-20H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound tested for the inhibition of GnRH-stimulated luteinizing hormone (LH) release in rat pituitary cells				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair