BDBM50101653 4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethylamino}-2,6-dimethyl-2H-pyridazin-3-one::CHEMBL80132

SMILES: COc1ccccc1N1CCN(CCNc2cc(C)nn(C)c2=O)CC1

InChI Key: InChIKey=COXFKNBPMUTWPD-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50101653 (4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethylam...) Show SMILES COc1ccccc1N1CCN(CCNc2cc(C)nn(C)c2=O)CC1 Show InChI InChI=1S/C19H27N5O2/c1-15-14-16(19(25)22(2)21-15)20-8-9-23-10-12-24(13-11-23)17-6-4-5-7-18(17)26-3/h4-7,14,20H,8-13H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico Farmaceutico e Tossicologico Curated by ChEMBL					Assay Description Binding affinity towards human cloned alpha1d-adrenoceptor using [3H]-prazosin as radioligand				J Med Chem 44: 2403-10 (2001) BindingDB Entry DOI: 10.7270/Q2WS8SHW
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50101653 (4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethylam...) Show SMILES COc1ccccc1N1CCN(CCNc2cc(C)nn(C)c2=O)CC1 Show InChI InChI=1S/C19H27N5O2/c1-15-14-16(19(25)22(2)21-15)20-8-9-23-10-12-24(13-11-23)17-6-4-5-7-18(17)26-3/h4-7,14,20H,8-13H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico Farmaceutico e Tossicologico Curated by ChEMBL					Assay Description Binding affinity towards human cloned alpha1A-adrenoceptor using [3H]-prazosin as radioligand				J Med Chem 44: 2403-10 (2001) BindingDB Entry DOI: 10.7270/Q2WS8SHW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50101653 (4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethylam...) Show SMILES COc1ccccc1N1CCN(CCNc2cc(C)nn(C)c2=O)CC1 Show InChI InChI=1S/C19H27N5O2/c1-15-14-16(19(25)22(2)21-15)20-8-9-23-10-12-24(13-11-23)17-6-4-5-7-18(17)26-3/h4-7,14,20H,8-13H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico Farmaceutico e Tossicologico Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				J Med Chem 44: 2403-10 (2001) BindingDB Entry DOI: 10.7270/Q2WS8SHW
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50101653 (4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethylam...) Show SMILES COc1ccccc1N1CCN(CCNc2cc(C)nn(C)c2=O)CC1 Show InChI InChI=1S/C19H27N5O2/c1-15-14-16(19(25)22(2)21-15)20-8-9-23-10-12-24(13-11-23)17-6-4-5-7-18(17)26-3/h4-7,14,20H,8-13H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico Farmaceutico e Tossicologico Curated by ChEMBL					Assay Description Binding affinity towards human cloned alpha1B-adrenoceptor using [3H]-prazosin as radioligand				J Med Chem 44: 2403-10 (2001) BindingDB Entry DOI: 10.7270/Q2WS8SHW
					More data for this Ligand-Target Pair