Found 5 hits for monomerid = 50101715 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50101715
![PNG](/data/jpeg/tenK5010/BindingDB_50101715.png) ((4-Benzylamino-cyclohexyl)-((S)-4'-methoxy-bipheny...)Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C1CCC(CC1)NCc1ccccc1)C(O)=O |wD:18.19,(18.21,3.1,;16.87,3.89,;15.54,3.1,;14.19,3.87,;12.88,3.08,;12.89,1.56,;14.22,.79,;15.55,1.56,;11.56,.77,;11.56,-.77,;10.22,-1.54,;8.89,-.77,;8.89,.77,;10.22,1.54,;7.56,-1.54,;8.64,-2.64,;6.46,-2.64,;6.21,-.77,;4.88,-1.54,;4.88,-3.08,;6.21,-3.83,;6.21,-5.37,;4.88,-6.14,;3.55,-5.37,;3.55,-3.85,;4.88,-7.68,;6.21,-8.47,;6.21,-10.01,;7.54,-10.76,;7.54,-12.3,;6.19,-13.07,;4.85,-12.3,;4.86,-10.76,;3.55,-.77,;2.22,-1.54,;3.55,.77,)| Show InChI InChI=1S/C28H32N2O5S/c1-35-25-15-9-21(10-16-25)22-11-17-26(18-12-22)36(33,34)30-27(28(31)32)23-7-13-24(14-8-23)29-19-20-5-3-2-4-6-20/h2-6,9-12,15-18,23-24,27,29-30H,7-8,13-14,19H2,1H3,(H,31,32)/t23?,24?,27-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration of the compound against Matrix metalloproteinase-1 |
Bioorg Med Chem Lett 11: 1975-9 (2001)
BindingDB Entry DOI: 10.7270/Q2S181SV |
More data for this Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50101715
![PNG](/data/jpeg/tenK5010/BindingDB_50101715.png) ((4-Benzylamino-cyclohexyl)-((S)-4'-methoxy-bipheny...)Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C1CCC(CC1)NCc1ccccc1)C(O)=O |wD:18.19,(18.21,3.1,;16.87,3.89,;15.54,3.1,;14.19,3.87,;12.88,3.08,;12.89,1.56,;14.22,.79,;15.55,1.56,;11.56,.77,;11.56,-.77,;10.22,-1.54,;8.89,-.77,;8.89,.77,;10.22,1.54,;7.56,-1.54,;8.64,-2.64,;6.46,-2.64,;6.21,-.77,;4.88,-1.54,;4.88,-3.08,;6.21,-3.83,;6.21,-5.37,;4.88,-6.14,;3.55,-5.37,;3.55,-3.85,;4.88,-7.68,;6.21,-8.47,;6.21,-10.01,;7.54,-10.76,;7.54,-12.3,;6.19,-13.07,;4.85,-12.3,;4.86,-10.76,;3.55,-.77,;2.22,-1.54,;3.55,.77,)| Show InChI InChI=1S/C28H32N2O5S/c1-35-25-15-9-21(10-16-25)22-11-17-26(18-12-22)36(33,34)30-27(28(31)32)23-7-13-24(14-8-23)29-19-20-5-3-2-4-6-20/h2-6,9-12,15-18,23-24,27,29-30H,7-8,13-14,19H2,1H3,(H,31,32)/t23?,24?,27-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 783 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration of the compound against Matrix metalloproteinase-3 |
Bioorg Med Chem Lett 11: 1975-9 (2001)
BindingDB Entry DOI: 10.7270/Q2S181SV |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-7 (MMP7)
(Homo sapiens (Human)) | BDBM50101715
![PNG](/data/jpeg/tenK5010/BindingDB_50101715.png) ((4-Benzylamino-cyclohexyl)-((S)-4'-methoxy-bipheny...)Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C1CCC(CC1)NCc1ccccc1)C(O)=O |wD:18.19,(18.21,3.1,;16.87,3.89,;15.54,3.1,;14.19,3.87,;12.88,3.08,;12.89,1.56,;14.22,.79,;15.55,1.56,;11.56,.77,;11.56,-.77,;10.22,-1.54,;8.89,-.77,;8.89,.77,;10.22,1.54,;7.56,-1.54,;8.64,-2.64,;6.46,-2.64,;6.21,-.77,;4.88,-1.54,;4.88,-3.08,;6.21,-3.83,;6.21,-5.37,;4.88,-6.14,;3.55,-5.37,;3.55,-3.85,;4.88,-7.68,;6.21,-8.47,;6.21,-10.01,;7.54,-10.76,;7.54,-12.3,;6.19,-13.07,;4.85,-12.3,;4.86,-10.76,;3.55,-.77,;2.22,-1.54,;3.55,.77,)| Show InChI InChI=1S/C28H32N2O5S/c1-35-25-15-9-21(10-16-25)22-11-17-26(18-12-22)36(33,34)30-27(28(31)32)23-7-13-24(14-8-23)29-19-20-5-3-2-4-6-20/h2-6,9-12,15-18,23-24,27,29-30H,7-8,13-14,19H2,1H3,(H,31,32)/t23?,24?,27-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration of the compound against Matrix metalloproteinase-7 |
Bioorg Med Chem Lett 11: 1975-9 (2001)
BindingDB Entry DOI: 10.7270/Q2S181SV |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50101715
![PNG](/data/jpeg/tenK5010/BindingDB_50101715.png) ((4-Benzylamino-cyclohexyl)-((S)-4'-methoxy-bipheny...)Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C1CCC(CC1)NCc1ccccc1)C(O)=O |wD:18.19,(18.21,3.1,;16.87,3.89,;15.54,3.1,;14.19,3.87,;12.88,3.08,;12.89,1.56,;14.22,.79,;15.55,1.56,;11.56,.77,;11.56,-.77,;10.22,-1.54,;8.89,-.77,;8.89,.77,;10.22,1.54,;7.56,-1.54,;8.64,-2.64,;6.46,-2.64,;6.21,-.77,;4.88,-1.54,;4.88,-3.08,;6.21,-3.83,;6.21,-5.37,;4.88,-6.14,;3.55,-5.37,;3.55,-3.85,;4.88,-7.68,;6.21,-8.47,;6.21,-10.01,;7.54,-10.76,;7.54,-12.3,;6.19,-13.07,;4.85,-12.3,;4.86,-10.76,;3.55,-.77,;2.22,-1.54,;3.55,.77,)| Show InChI InChI=1S/C28H32N2O5S/c1-35-25-15-9-21(10-16-25)22-11-17-26(18-12-22)36(33,34)30-27(28(31)32)23-7-13-24(14-8-23)29-19-20-5-3-2-4-6-20/h2-6,9-12,15-18,23-24,27,29-30H,7-8,13-14,19H2,1H3,(H,31,32)/t23?,24?,27-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2 |
Bioorg Med Chem Lett 11: 1975-9 (2001)
BindingDB Entry DOI: 10.7270/Q2S181SV |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50101715
![PNG](/data/jpeg/tenK5010/BindingDB_50101715.png) ((4-Benzylamino-cyclohexyl)-((S)-4'-methoxy-bipheny...)Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C1CCC(CC1)NCc1ccccc1)C(O)=O |wD:18.19,(18.21,3.1,;16.87,3.89,;15.54,3.1,;14.19,3.87,;12.88,3.08,;12.89,1.56,;14.22,.79,;15.55,1.56,;11.56,.77,;11.56,-.77,;10.22,-1.54,;8.89,-.77,;8.89,.77,;10.22,1.54,;7.56,-1.54,;8.64,-2.64,;6.46,-2.64,;6.21,-.77,;4.88,-1.54,;4.88,-3.08,;6.21,-3.83,;6.21,-5.37,;4.88,-6.14,;3.55,-5.37,;3.55,-3.85,;4.88,-7.68,;6.21,-8.47,;6.21,-10.01,;7.54,-10.76,;7.54,-12.3,;6.19,-13.07,;4.85,-12.3,;4.86,-10.76,;3.55,-.77,;2.22,-1.54,;3.55,.77,)| Show InChI InChI=1S/C28H32N2O5S/c1-35-25-15-9-21(10-16-25)22-11-17-26(18-12-22)36(33,34)30-27(28(31)32)23-7-13-24(14-8-23)29-19-20-5-3-2-4-6-20/h2-6,9-12,15-18,23-24,27,29-30H,7-8,13-14,19H2,1H3,(H,31,32)/t23?,24?,27-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13 |
Bioorg Med Chem Lett 11: 1975-9 (2001)
BindingDB Entry DOI: 10.7270/Q2S181SV |
More data for this Ligand-Target Pair | |