BDBM50101852 (3-{(1R,2S,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl)-3-hydroxy-but-1-enyl]-3-hydroxy-5-oxo-cyclopentylsulfanyl}-propylsulfanyl)-acetic acid::CHEMBL64557
SMILES: CCOCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)c1
InChI Key: InChIKey=KSPWVOZYNMKFCC-FYHHZQEOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50101852 ((3-{(1R,2S,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP4 receptor in CHO cells expressing prostanoid receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50101852 ((3-{(1R,2S,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP3 receptor in CHO cells expressing prostanoid receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50101852 ((3-{(1R,2S,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Evaluated for its competitive binding affinity towards human Prostanoid IP receptor in CHO cells | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50101852 ((3-{(1R,2S,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP2 receptor in CHO cells expressing prostanoid receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50101852 ((3-{(1R,2S,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP1 receptor in CHO cells expressing prostanoid receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 receptor (Mus musculus (Mouse)) | BDBM50101852 ((3-{(1R,2S,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair |