null

SMILES: CS(=O)(=O)N1CCC(CC1)NC(=O)Nc1cnc2[nH]ccc2n1

InChI Key: InChIKey=APGTVHPARWDUFA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50102641 (CHEMBL3335679) Show SMILES CS(=O)(=O)N1CCC(CC1)NC(=O)Nc1cnc2[nH]ccc2n1 Show InChI InChI=1S/C13H18N6O3S/c1-23(21,22)19-6-3-9(4-7-19)16-13(20)18-11-8-15-12-10(17-11)2-5-14-12/h2,5,8-9H,3-4,6-7H2,1H3,(H,14,15)(H2,16,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...				Bioorg Med Chem Lett 24: 4969-75 (2014) Article DOI: 10.1016/j.bmcl.2014.09.031 BindingDB Entry DOI: 10.7270/Q25X2BPB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50102641 (CHEMBL3335679) Show SMILES CS(=O)(=O)N1CCC(CC1)NC(=O)Nc1cnc2[nH]ccc2n1 Show InChI InChI=1S/C13H18N6O3S/c1-23(21,22)19-6-3-9(4-7-19)16-13(20)18-11-8-15-12-10(17-11)2-5-14-12/h2,5,8-9H,3-4,6-7H2,1H3,(H,14,15)(H2,16,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...				Bioorg Med Chem Lett 24: 4969-75 (2014) Article DOI: 10.1016/j.bmcl.2014.09.031 BindingDB Entry DOI: 10.7270/Q25X2BPB
					More data for this Ligand-Target Pair