BDBM50103159 5-Dimethylamino-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide::CHEMBL419995

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)N(C)C

InChI Key: InChIKey=WYWAKLNLTJVWAB-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50103159 (5-Dimethylamino-N-hydroxy-2-[(4-methoxy-benzenesul...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)N(C)C Show InChI InChI=1S/C23H26N4O5S/c1-16-12-18(26(2)3)13-21(23(28)25-29)22(16)27(15-17-6-5-11-24-14-17)33(30,31)20-9-7-19(32-4)8-10-20/h5-14,29H,15H2,1-4H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50103159 (5-Dimethylamino-N-hydroxy-2-[(4-methoxy-benzenesul...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)N(C)C Show InChI InChI=1S/C23H26N4O5S/c1-16-12-18(26(2)3)13-21(23(28)25-29)22(16)27(15-17-6-5-11-24-14-17)33(30,31)20-9-7-19(32-4)8-10-20/h5-14,29H,15H2,1-4H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotease-1				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50103159 (5-Dimethylamino-N-hydroxy-2-[(4-methoxy-benzenesul...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)N(C)C Show InChI InChI=1S/C23H26N4O5S/c1-16-12-18(26(2)3)13-21(23(28)25-29)22(16)27(15-17-6-5-11-24-14-17)33(30,31)20-9-7-19(32-4)8-10-20/h5-14,29H,15H2,1-4H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	633	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of TNF-alpha converting enzyme (TACE)				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50103159 (5-Dimethylamino-N-hydroxy-2-[(4-methoxy-benzenesul...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)N(C)C Show InChI InChI=1S/C23H26N4O5S/c1-16-12-18(26(2)3)13-21(23(28)25-29)22(16)27(15-17-6-5-11-24-14-17)33(30,31)20-9-7-19(32-4)8-10-20/h5-14,29H,15H2,1-4H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro ability to inhibit matrix metalloprotease-9.				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair