BDBM50103165 CHEMBL68212::N-Hydroxy-3-methyl-2-{methyl-[4-(pyridin-4-yloxy)-benzenesulfonyl]-amino}-benzamide

SMILES: CN(c1c(C)cccc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1

InChI Key: InChIKey=QYEGLTVXUKXPSD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50103165 (CHEMBL68212 | N-Hydroxy-3-methyl-2-{methyl-[4-(pyr...) Show SMILES CN(c1c(C)cccc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C20H19N3O5S/c1-14-4-3-5-18(20(24)22-25)19(14)23(2)29(26,27)17-8-6-15(7-9-17)28-16-10-12-21-13-11-16/h3-13,25H,1-2H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotease-1				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50103165 (CHEMBL68212 | N-Hydroxy-3-methyl-2-{methyl-[4-(pyr...) Show SMILES CN(c1c(C)cccc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C20H19N3O5S/c1-14-4-3-5-18(20(24)22-25)19(14)23(2)29(26,27)17-8-6-15(7-9-17)28-16-10-12-21-13-11-16/h3-13,25H,1-2H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50103165 (CHEMBL68212 | N-Hydroxy-3-methyl-2-{methyl-[4-(pyr...) Show SMILES CN(c1c(C)cccc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C20H19N3O5S/c1-14-4-3-5-18(20(24)22-25)19(14)23(2)29(26,27)17-8-6-15(7-9-17)28-16-10-12-21-13-11-16/h3-13,25H,1-2H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro ability to inhibit matrix metalloprotease-9.				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair