BDBM50103167 2-[(4'-Benzyloxy-biphenyl-4-sulfonyl)-methyl-amino]-5-bromo-N-hydroxy-3-methyl-benzamide::CHEMBL67590

SMILES: CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=FJRQWHSKVHCEKG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50103167 (2-[(4'-Benzyloxy-biphenyl-4-sulfonyl)-methyl-amino...) Show SMILES CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C28H25BrN2O5S/c1-19-16-23(29)17-26(28(32)30-33)27(19)31(2)37(34,35)25-14-10-22(11-15-25)21-8-12-24(13-9-21)36-18-20-6-4-3-5-7-20/h3-17,33H,18H2,1-2H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of TNF-alpha converting enzyme (TACE)				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50103167 (2-[(4'-Benzyloxy-biphenyl-4-sulfonyl)-methyl-amino...) Show SMILES CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C28H25BrN2O5S/c1-19-16-23(29)17-26(28(32)30-33)27(19)31(2)37(34,35)25-14-10-22(11-15-25)21-8-12-24(13-9-21)36-18-20-6-4-3-5-7-20/h3-17,33H,18H2,1-2H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro ability to inhibit matrix metalloprotease-9.				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50103167 (2-[(4'-Benzyloxy-biphenyl-4-sulfonyl)-methyl-amino...) Show SMILES CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C28H25BrN2O5S/c1-19-16-23(29)17-26(28(32)30-33)27(19)31(2)37(34,35)25-14-10-22(11-15-25)21-8-12-24(13-9-21)36-18-20-6-4-3-5-7-20/h3-17,33H,18H2,1-2H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair