BDBM50103175 CHEMBL71645::N-Hydroxy-2-[(4'-methoxy-biphenyl-4-sulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide::N-hydroxy-2-(4'-methoxy-N-(pyridin-3-ylmethyl)biphenyl-4-ylsulfonamido)-3-methylbenzamide

SMILES: COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO

InChI Key: InChIKey=WMBVCTBFQRRSBU-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50103175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50103175 (CHEMBL71645 | N-Hydroxy-2-[(4'-methoxy-biphenyl-4-...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-5-3-7-25(27(31)29-32)26(19)30(18-20-6-4-16-28-17-20)36(33,34)24-14-10-22(11-15-24)21-8-12-23(35-2)13-9-21/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem 16: 8781-94 (2008) Article DOI: 10.1016/j.bmc.2008.08.058 BindingDB Entry DOI: 10.7270/Q2JD4WM2
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50103175 (CHEMBL71645 | N-Hydroxy-2-[(4'-methoxy-biphenyl-4-...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-5-3-7-25(27(31)29-32)26(19)30(18-20-6-4-16-28-17-20)36(33,34)24-14-10-22(11-15-24)21-8-12-23(35-2)13-9-21/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 16: 8781-94 (2008) Article DOI: 10.1016/j.bmc.2008.08.058 BindingDB Entry DOI: 10.7270/Q2JD4WM2
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50103175 (CHEMBL71645 | N-Hydroxy-2-[(4'-methoxy-biphenyl-4-...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-5-3-7-25(27(31)29-32)26(19)30(18-20-6-4-16-28-17-20)36(33,34)24-14-10-22(11-15-24)21-8-12-23(35-2)13-9-21/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro ability to inhibit matrix metalloprotease-9.				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50103175 (CHEMBL71645 | N-Hydroxy-2-[(4'-methoxy-biphenyl-4-...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-5-3-7-25(27(31)29-32)26(19)30(18-20-6-4-16-28-17-20)36(33,34)24-14-10-22(11-15-24)21-8-12-23(35-2)13-9-21/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50103175 (CHEMBL71645 | N-Hydroxy-2-[(4'-methoxy-biphenyl-4-...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-5-3-7-25(27(31)29-32)26(19)30(18-20-6-4-16-28-17-20)36(33,34)24-14-10-22(11-15-24)21-8-12-23(35-2)13-9-21/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotease-1				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50103175 (CHEMBL71645 | N-Hydroxy-2-[(4'-methoxy-biphenyl-4-...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-5-3-7-25(27(31)29-32)26(19)30(18-20-6-4-16-28-17-20)36(33,34)24-14-10-22(11-15-24)21-8-12-23(35-2)13-9-21/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of MMP1				Bioorg Med Chem 16: 8781-94 (2008) Article DOI: 10.1016/j.bmc.2008.08.058 BindingDB Entry DOI: 10.7270/Q2JD4WM2
					More data for this Ligand-Target Pair