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SMILES: O=C1NC(=O)C(=C1c1cn(CCCN2CCOCC2)c2ccccc12)c1nnc2ccccn12

InChI Key: InChIKey=NHBBJBOGWGWTRG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103374   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM50103374
PNG
(CHEMBL3398205)
Show SMILES O=C1NC(=O)C(=C1c1cn(CCCN2CCOCC2)c2ccccc12)c1nnc2ccccn12 |c:5|
Show InChI InChI=1S/C25H24N6O3/c32-24-21(22(25(33)26-24)23-28-27-20-8-3-4-11-31(20)23)18-16-30(19-7-2-1-6-17(18)19)10-5-9-29-12-14-34-15-13-29/h1-4,6-8,11,16H,5,9-10,12-15H2,(H,26,32,33)
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged GSK-3beta (unknown origin) expressed in Escherichia coli strain BL21-Codon Plus (DE3) using Ser/Thr 9 peptide su...

Bioorg Med Chem 23: 1179-88 (2015)


Article DOI: 10.1016/j.bmc.2014.12.026
BindingDB Entry DOI: 10.7270/Q23X88F1
More data for this
Ligand-Target Pair