BDBM50103509 1-(4-Azido-phenyl)-5-p-tolyl-3-trifluoromethyl-1H-pyrazole::CHEMBL104502
SMILES: Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)N=[N+]=[N-])C(F)(F)F
InChI Key: InChIKey=UBOLXNPTLLXANI-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human)) | BDBM50103509![]() (1-(4-Azido-phenyl)-5-p-tolyl-3-trifluoromethyl-1H-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Inhibitory concentration against Prostaglandin G/H synthase 1 | J Med Chem 44: 3039-42 (2001) BindingDB Entry DOI: 10.7270/Q22806W4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep)) | BDBM50103509![]() (1-(4-Azido-phenyl)-5-p-tolyl-3-trifluoromethyl-1H-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The M.S University of Baroda Curated by ChEMBL | Assay Description Inhibition of ovine COX-2 | Eur J Med Chem 162: 1-17 (2019) Article DOI: 10.1016/j.ejmech.2018.10.054 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase (Homo sapiens (Human)) | BDBM50103509![]() (1-(4-Azido-phenyl)-5-p-tolyl-3-trifluoromethyl-1H-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Inhibitory concentration against Prostaglandin G/H synthase 2 | J Med Chem 44: 3039-42 (2001) BindingDB Entry DOI: 10.7270/Q22806W4 | |||||||||||
More data for this Ligand-Target Pair |