BDBM50103704 CHEMBL73990::N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-3-yl)-phenyl]-4-methoxy-N-methyl-benzenesulfonamide
SMILES: COc1ccc(cc1)S(=O)(=O)N(C)c1ccc(cc1)-c1cc(N)n(n1)-c1ccc(C)cc1
InChI Key: InChIKey=LQGYOAIFOSBVLV-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuropeptide Y receptor type 5 (Homo sapiens (Human)) | BDBM50103704 (CHEMBL73990 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-3...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity of the compound against human Neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligand | Bioorg Med Chem Lett 11: 2283-6 (2001) BindingDB Entry DOI: 10.7270/Q2NZ86WB | |||||||||||
More data for this Ligand-Target Pair |