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SMILES: Nc1cc(nn1-c1ccc(cc1)C(F)(F)F)C1CCC(CNS(=O)(=O)c2ccccc2N)CC1

InChI Key: InChIKey=PIMGSWUKUUYMBZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103715   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50103715
PNG
(2-Amino-N-{4-[5-amino-1-(4-trifluoromethyl-phenyl)...)
Show SMILES Nc1cc(nn1-c1ccc(cc1)C(F)(F)F)C1CCC(CNS(=O)(=O)c2ccccc2N)CC1 |(-4.59,.2,;-3.68,1.44,;-2.14,1.44,;-1.67,2.91,;-2.91,3.81,;-4.16,2.91,;-5.61,3.39,;-5.93,4.88,;-7.4,5.36,;-8.54,4.35,;-8.22,2.82,;-6.75,2.35,;-10.01,4.82,;-10.59,6.31,;-11.33,3.93,;-11.32,5.23,;-.2,3.39,;.12,4.89,;1.59,5.36,;2.73,4.33,;4.19,4.79,;5.32,3.77,;6.79,4.23,;7.11,5.72,;8.28,4.63,;7.93,3.19,;7.6,1.69,;8.74,.67,;10.2,1.13,;10.53,2.63,;9.39,3.67,;9.7,5.16,;2.4,2.82,;.94,2.35,)|
Show InChI InChI=1S/C23H26F3N5O2S/c24-23(25,26)17-9-11-18(12-10-17)31-22(28)13-20(30-31)16-7-5-15(6-8-16)14-29-34(32,33)21-4-2-1-3-19(21)27/h1-4,9-13,15-16,29H,5-8,14,27-28H2
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 20n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand

Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair