BDBM50104689 4-Hydroxy-5-hydroxymethyl-3-(3-phenyl-acryloyl)-5H-furan-2-one::CHEMBL113497

SMILES: OCc1oc(O)c(C(=O)C=Cc2ccccc2)c1O

InChI Key: InChIKey=OOFCSKOSHDSREE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104689   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM50104689 (4-Hydroxy-5-hydroxymethyl-3-(3-phenyl-acryloyl)-5H...) Show SMILES OCc1oc(O)c(C(=O)C=Cc2ccccc2)c1O |w:10.10| Show InChI InChI=1S/C14H12O5/c15-8-11-13(17)12(14(18)19-11)10(16)7-6-9-4-2-1-3-5-9/h1-7,15,17-18H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku University Curated by ChEMBL					Assay Description Inhibitory activity against vaccinia VH1-related phosphatase(VHR)				J Med Chem 44: 3216-22 (2001) BindingDB Entry DOI: 10.7270/Q2WD3ZVR
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Mus musculus)	BDBM50104689 (4-Hydroxy-5-hydroxymethyl-3-(3-phenyl-acryloyl)-5H...) Show SMILES OCc1oc(O)c(C(=O)C=Cc2ccccc2)c1O |w:10.10| Show InChI InChI=1S/C14H12O5/c15-8-11-13(17)12(14(18)19-11)10(16)7-6-9-4-2-1-3-5-9/h1-7,15,17-18H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku University Curated by ChEMBL					Assay Description Inhibitory activity against cell division cycle 25B				J Med Chem 44: 3216-22 (2001) BindingDB Entry DOI: 10.7270/Q2WD3ZVR
					More data for this Ligand-Target Pair