BDBM50105632 1H-Benzoimidazole-4-carboxylic acid 1-methyl-piperidin-4-yl ester::CHEMBL279823

SMILES: CN1CCC(CC1)OC(=O)c1cccc2nc[nH]c12

InChI Key: InChIKey=GVHZBCMYHZGMMR-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50105632 (1H-Benzoimidazole-4-carboxylic acid 1-methyl-piper...) Show SMILES CN1CCC(CC1)OC(=O)c1cccc2nc[nH]c12 Show InChI InChI=1S/C14H17N3O2/c1-17-7-5-10(6-8-17)19-14(18)11-3-2-4-12-13(11)16-9-15-12/h2-4,9-10H,5-8H2,1H3,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 6: 1195-1198 (1996) Article DOI: 10.1016/0960-894X(96)00200-4 BindingDB Entry DOI: 10.7270/Q23J3DGF
					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50105632 (1H-Benzoimidazole-4-carboxylic acid 1-methyl-piper...) Show SMILES CN1CCC(CC1)OC(=O)c1cccc2nc[nH]c12 Show InChI InChI=1S/C14H17N3O2/c1-17-7-5-10(6-8-17)19-14(18)11-3-2-4-12-13(11)16-9-15-12/h2-4,9-10H,5-8H2,1H3,(H,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from rat striatum 5-hydroxytryptamine 4 receptor				Bioorg Med Chem Lett 6: 1195-1198 (1996) Article DOI: 10.1016/0960-894X(96)00200-4 BindingDB Entry DOI: 10.7270/Q23J3DGF
					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50105632 (1H-Benzoimidazole-4-carboxylic acid 1-methyl-piper...) Show SMILES CN1CCC(CC1)OC(=O)c1cccc2nc[nH]c12 Show InChI InChI=1S/C14H17N3O2/c1-17-7-5-10(6-8-17)19-14(18)11-3-2-4-12-13(11)16-9-15-12/h2-4,9-10H,5-8H2,1H3,(H,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity to 5-hydroxytryptamine 4 receptor in rat striatum membrane				Bioorg Med Chem Lett 11: 2807-11 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q29G5M3X
					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50105632 (1H-Benzoimidazole-4-carboxylic acid 1-methyl-piper...) Show SMILES CN1CCC(CC1)OC(=O)c1cccc2nc[nH]c12 Show InChI InChI=1S/C14H17N3O2/c1-17-7-5-10(6-8-17)19-14(18)11-3-2-4-12-13(11)16-9-15-12/h2-4,9-10H,5-8H2,1H3,(H,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity to 5-hydroxytryptamine 4 receptor using [3H]-GR-113,808 as radioligand in rat striatum membrane				J Med Chem 45: 4806-15 (2002) BindingDB Entry DOI: 10.7270/Q2BZ65D3
					More data for this Ligand-Target Pair