BDBM50105954 1-(4-tert-Butyl-phenyl)-4-[(2-hydroxy-4-sulfo-naphthalen-1-yl)-hydrazono]-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid tert-butyl ester::CHEMBL125777

SMILES: CC(C)(C)OC(=O)c1[nH]n(-c2ccc(cc2)C(C)(C)C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O

InChI Key: InChIKey=HVIVPGDDTSYQQR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105954 (1-(4-tert-Butyl-phenyl)-4-[(2-hydroxy-4-sulfo-naph...) Show SMILES CC(C)(C)OC(=O)c1[nH]n(-c2ccc(cc2)C(C)(C)C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:24.26| Show InChI InChI=1S/C28H30N4O7S/c1-27(2,3)16-11-13-17(14-12-16)32-25(34)23(24(31-32)26(35)39-28(4,5)6)30-29-22-19-10-8-7-9-18(19)21(15-20(22)33)40(36,37)38/h7-15,31,33H,1-6H3,(H,36,37,38)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair