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SMILES: OC(=O)c1cc2ccccc2c(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1O

InChI Key: InChIKey=MVQBFZXBLLMXGS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105956   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thrombopoietin receptor


(Homo sapiens (Human))		BDBM50105956
PNG
(3-Hydroxy-4-(2-hydroxy-4-sulfo-naphthalen-1-ylazo)...)
Show SMILES OC(=O)c1cc2ccccc2c(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1O |w:12.12|
Show InChI InChI=1S/C21H14N2O7S/c24-16-10-17(31(28,29)30)13-7-3-4-8-14(13)18(16)22-23-19-12-6-2-1-5-11(12)9-15(20(19)25)21(26)27/h1-10,24-25H,(H,26,27)(H,28,29,30)
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PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells

J Med Chem 44: 3730-45 (2001)


BindingDB Entry DOI: 10.7270/Q2MP52KF
More data for this
Ligand-Target Pair