BDBM50106065 3-Amino-1H-indazole-5-carboxylic acid [(S)-phenyl-(2'-sulfamoyl-biphenyl-4-ylcarbamoyl)-methyl]-amide::CHEMBL101787

SMILES: Nc1[nH]nc2ccc(cc12)C(=O)N[C@H](C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1ccccc1

InChI Key: InChIKey=JRWNGSOUJJAUPR-VWLOTQADSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50106065 (3-Amino-1H-indazole-5-carboxylic acid [(S)-phenyl-...) Show SMILES Nc1[nH]nc2ccc(cc12)C(=O)N[C@H](C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1ccccc1 Show InChI InChI=1S/C28H24N6O4S/c29-26-22-16-19(12-15-23(22)33-34-26)27(35)32-25(18-6-2-1-3-7-18)28(36)31-20-13-10-17(11-14-20)21-8-4-5-9-24(21)39(30,37)38/h1-16,25H,(H,31,36)(H,32,35)(H3,29,33,34)(H2,30,37,38)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor Xa.				Bioorg Med Chem Lett 11: 2947-50 (2001) BindingDB Entry DOI: 10.7270/Q27H1HW6
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50106065 (3-Amino-1H-indazole-5-carboxylic acid [(S)-phenyl-...) Show SMILES Nc1[nH]nc2ccc(cc12)C(=O)N[C@H](C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1ccccc1 Show InChI InChI=1S/C28H24N6O4S/c29-26-22-16-19(12-15-23(22)33-34-26)27(35)32-25(18-6-2-1-3-7-18)28(36)31-20-13-10-17(11-14-20)21-8-4-5-9-24(21)39(30,37)38/h1-16,25H,(H,31,36)(H,32,35)(H3,29,33,34)(H2,30,37,38)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of human thrombin.				Bioorg Med Chem Lett 11: 2947-50 (2001) BindingDB Entry DOI: 10.7270/Q27H1HW6
					More data for this Ligand-Target Pair