BDBM50106393 1-(pyridin-4-yl)piperazine::1-Pyridin-4-yl-piperazine::CHEMBL339069

SMILES: C1CN(CCN1)c1ccncc1

InChI Key: InChIKey=OQZBAQXTXNIPRA-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50106393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50106393 (1-(pyridin-4-yl)piperazine | 1-Pyridin-4-yl-pipera...) Show SMILES C1CN(CCN1)c1ccncc1 Show InChI InChI=1S/C9H13N3/c1-3-10-4-2-9(1)12-7-5-11-6-8-12/h1-4,11H,5-8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Binding affinity against nicotinic receptors from rat brain using [3H]cystine as radioligand				J Med Chem 44: 3946-55 (2001) Article DOI: 10.1021/jm010901y BindingDB Entry DOI: 10.7270/Q2B56NH9
					More data for this Ligand-Target Pair
Neutrophil cytosol factor 1 (Homo sapiens)	BDBM50106393 (1-(pyridin-4-yl)piperazine | 1-Pyridin-4-yl-pipera...) Show SMILES C1CN(CCN1)c1ccncc1 Show InChI InChI=1S/C9H13N3/c1-3-10-4-2-9(1)12-7-5-11-6-8-12/h1-4,11H,5-8H2	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.02E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...				J Med Chem 63: 1156-1177 (2020) Article DOI: 10.1021/acs.jmedchem.9b01492
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM50106393 (1-(pyridin-4-yl)piperazine | 1-Pyridin-4-yl-pipera...) Show SMILES C1CN(CCN1)c1ccncc1 Show InChI InChI=1S/C9H13N3/c1-3-10-4-2-9(1)12-7-5-11-6-8-12/h1-4,11H,5-8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of PLD1 in human Calu1 cells				Bioorg Med Chem Lett 19: 2240-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.125 BindingDB Entry DOI: 10.7270/Q2F76CG5
					More data for this Ligand-Target Pair