BDBM50106564 2-[(3,5-Difluoro-benzyl)-hydroxy-phosphinoylmethyl]-pentanedioic acid::CHEMBL336338

SMILES: OC(=O)CCC(CP(O)(=O)Cc1cc(F)cc(F)c1)C(O)=O

InChI Key: InChIKey=LKGPZJOMEHGIRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106564   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate carboxypeptidase II (Rattus norvegicus)	BDBM50106564 (2-[(3,5-Difluoro-benzyl)-hydroxy-phosphinoylmethyl...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1cc(F)cc(F)c1)C(O)=O Show InChI InChI=1S/C13H15F2O6P/c14-10-3-8(4-11(15)5-10)6-22(20,21)7-9(13(18)19)1-2-12(16)17/h3-5,9H,1-2,6-7H2,(H,16,17)(H,18,19)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair