BDBM50106678 2-Pentyl-5,6-diphenyl-2H-pyridazin-3-one::CHEMBL137235

SMILES: CCCCCn1nc(-c2ccccc2)c(cc1=O)-c1ccccc1

InChI Key: InChIKey=NGPIXWGYSVKHML-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106678 (2-Pentyl-5,6-diphenyl-2H-pyridazin-3-one | CHEMBL1...) Show SMILES CCCCCn1nc(-c2ccccc2)c(cc1=O)-c1ccccc1 Show InChI InChI=1S/C21H22N2O/c1-2-3-10-15-23-20(24)16-19(17-11-6-4-7-12-17)21(22-23)18-13-8-5-9-14-18/h4-9,11-14,16H,2-3,10,15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
					More data for this Ligand-Target Pair