BDBM50106699 2-Cyclopentyl-5,6-diphenyl-2H-pyridazin-3-one::CHEMBL132757

SMILES: O=c1cc(-c2ccccc2)c(nn1C1CCCC1)-c1ccccc1

InChI Key: InChIKey=VARIPBRBEAUYRV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50106699 (2-Cyclopentyl-5,6-diphenyl-2H-pyridazin-3-one | CH...) Show SMILES O=c1cc(-c2ccccc2)c(nn1C1CCCC1)-c1ccccc1 Show InChI InChI=1S/C21H20N2O/c24-20-15-19(16-9-3-1-4-10-16)21(17-11-5-2-6-12-17)22-23(20)18-13-7-8-14-18/h1-6,9-12,15,18H,7-8,13-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
					More data for this Ligand-Target Pair