BDBM50106832 CHEMBL103117::N-(2-Hydroxy-5-{(R)-1-hydroxy-2-[2-phenyl-1-(4-trifluoromethoxy-phenyl)-ethylamino]-ethyl}-phenyl)-methanesulfonamide
SMILES: CS(=O)(=O)Nc1cc(ccc1O)[C@@H](O)CNC(Cc1ccccc1)c1ccc(OC(F)(F)F)cc1
InChI Key: InChIKey=LTTRPGNJRAQBTP-AKRCKQFNSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-3 adrenergic receptor (Homo sapiens (Human)) | BDBM50106832![]() (CHEMBL103117 | N-(2-Hydroxy-5-{(R)-1-hydroxy-2-[2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity to CHO cells expressing the cloned human beta-3 adrenergic receptor in the presence of [125I]-iodocyanopindolol | Bioorg Med Chem Lett 11: 3041-4 (2001) BindingDB Entry DOI: 10.7270/Q2794402 | |||||||||||
More data for this Ligand-Target Pair |