null

SMILES: NC(=O)C1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=YMOPRQZMFXJLSA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50107748 (CHEMBL3600831) Show SMILES NC(=O)C1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H26ClN3O2/c28-24-7-4-21(5-8-24)23-6-10-25(30-19-23)9-1-20-2-11-26(12-3-20)33-18-17-31-15-13-22(14-16-31)27(29)32/h2-8,10-12,19,22H,13-18H2,(H2,29,32)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of muscarinic M1 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107748 (CHEMBL3600831) Show SMILES NC(=O)C1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H26ClN3O2/c28-24-7-4-21(5-8-24)23-6-10-25(30-19-23)9-1-20-2-11-26(12-3-20)33-18-17-31-15-13-22(14-16-31)27(29)32/h2-8,10-12,19,22H,13-18H2,(H2,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50107748 (CHEMBL3600831) Show SMILES NC(=O)C1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H26ClN3O2/c28-24-7-4-21(5-8-24)23-6-10-25(30-19-23)9-1-20-2-11-26(12-3-20)33-18-17-31-15-13-22(14-16-31)27(29)32/h2-8,10-12,19,22H,13-18H2,(H2,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of CYP2D6 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50107748 (CHEMBL3600831) Show SMILES NC(=O)C1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H26ClN3O2/c28-24-7-4-21(5-8-24)23-6-10-25(30-19-23)9-1-20-2-11-26(12-3-20)33-18-17-31-15-13-22(14-16-31)27(29)32/h2-8,10-12,19,22H,13-18H2,(H2,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of 5HT2A receptor (unknown origin)				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair