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BDBM50107880 4-{2-[(5,6-Dimethoxy-indan-2-yl)-propyl-amino]-ethyl}-thiazol-2-ylamine::CHEMBL141614

SMILES: CCCN(CCc1csc(N)n1)C1Cc2cc(OC)c(OC)cc2C1

InChI Key: InChIKey=BRFFPGSHDFIFKS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107880   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(3) dopamine receptor


(Rattus norvegicus (Rat))
BDBM50107880
PNG
(4-{2-[(5,6-Dimethoxy-indan-2-yl)-propyl-amino]-eth...)
Show SMILES CCCN(CCc1csc(N)n1)C1Cc2cc(OC)c(OC)cc2C1
Show InChI InChI=1S/C19H27N3O2S/c1-4-6-22(7-5-15-12-25-19(20)21-15)16-8-13-10-17(23-2)18(24-3)11-14(13)9-16/h10-12,16H,4-9H2,1-3H3,(H2,20,21)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
136n/an/an/an/an/an/an/an/a



Pharmacia

Curated by ChEMBL


Assay Description
Affinity at rat D3 dopamine receptor on CHO cell membranes by [3H]-spiperone displacement.


J Med Chem 44: 4716-32 (2001)


BindingDB Entry DOI: 10.7270/Q2ZP45D5
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))
BDBM50107880
PNG
(4-{2-[(5,6-Dimethoxy-indan-2-yl)-propyl-amino]-eth...)
Show SMILES CCCN(CCc1csc(N)n1)C1Cc2cc(OC)c(OC)cc2C1
Show InChI InChI=1S/C19H27N3O2S/c1-4-6-22(7-5-15-12-25-19(20)21-15)16-8-13-10-17(23-2)18(24-3)11-14(13)9-16/h10-12,16H,4-9H2,1-3H3,(H2,20,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
265n/an/an/an/an/an/an/an/a



Pharmacia

Curated by ChEMBL


Assay Description
Affinity at D2 dopamine receptor on CHO cell membranes by [3H]-PNU-86170 displacement.


J Med Chem 44: 4716-32 (2001)


BindingDB Entry DOI: 10.7270/Q2ZP45D5
More data for this
Ligand-Target Pair