BDBM50107954 2-Amino-3-(3-hydroxy-isoxazol-4-yl)-propionic acid::CHEMBL317234
SMILES: NC(Cc1co[nH]c1=O)C(O)=O
InChI Key: InChIKey=ZKLGQYGPVBFAQQ-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50107954 (2-Amino-3-(3-hydroxy-isoxazol-4-yl)-propionic acid...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Binding affinity for Excitatory amino acid transporter 2 (EAAT-2) in Glu uptake system | J Med Chem 45: 19-31 (2001) BindingDB Entry DOI: 10.7270/Q2KH0MMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50107954 (2-Amino-3-(3-hydroxy-isoxazol-4-yl)-propionic acid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Binding affinity for Excitatory amino acid transporter 3 (EAAT-3) in Glu uptake system | J Med Chem 45: 19-31 (2001) BindingDB Entry DOI: 10.7270/Q2KH0MMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50107954 (2-Amino-3-(3-hydroxy-isoxazol-4-yl)-propionic acid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Binding affinity for Excitatory amino acid transporter 1 (EAAT-1) in Glu uptake system | J Med Chem 45: 19-31 (2001) BindingDB Entry DOI: 10.7270/Q2KH0MMK | |||||||||||
More data for this Ligand-Target Pair |