BDBM50108099 CHEMBL3601204

SMILES: CCc1n[nH]c2cc(OCCNC[C@H](O)c3cccc(NS(C)(=O)=O)c3)ccc12

InChI Key: InChIKey=MBJXNRMFNNYLBI-FQEVSTJZSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50108099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50108099 (CHEMBL3601204) Show SMILES CCc1n[nH]c2cc(OCCNC[C@H](O)c3cccc(NS(C)(=O)=O)c3)ccc12 |r| Show InChI InChI=1S/C20H26N4O4S/c1-3-18-17-8-7-16(12-19(17)23-22-18)28-10-9-21-13-20(25)14-5-4-6-15(11-14)24-29(2,26)27/h4-8,11-12,20-21,24-25H,3,9-10,13H2,1-2H3,(H,22,23)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Agonist activity at human recombinant beta3-adrenergic receptor expressed in CHO cells assessed as increase of cAMP level after 30 mins				J Med Chem 58: 6048-57 (2015) BindingDB Entry DOI: 10.7270/Q2NG4SDR
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50108099 (CHEMBL3601204) Show SMILES CCc1n[nH]c2cc(OCCNC[C@H](O)c3cccc(NS(C)(=O)=O)c3)ccc12 |r| Show InChI InChI=1S/C20H26N4O4S/c1-3-18-17-8-7-16(12-19(17)23-22-18)28-10-9-21-13-20(25)14-5-4-6-15(11-14)24-29(2,26)27/h4-8,11-12,20-21,24-25H,3,9-10,13H2,1-2H3,(H,22,23)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Agonist activity at human beta1-adrenergic receptor expressed in CHO cells assessed as increase of cAMP level after 30 mins				J Med Chem 58: 6048-57 (2015) BindingDB Entry DOI: 10.7270/Q2NG4SDR
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50108099 (CHEMBL3601204) Show SMILES CCc1n[nH]c2cc(OCCNC[C@H](O)c3cccc(NS(C)(=O)=O)c3)ccc12 |r| Show InChI InChI=1S/C20H26N4O4S/c1-3-18-17-8-7-16(12-19(17)23-22-18)28-10-9-21-13-20(25)14-5-4-6-15(11-14)24-29(2,26)27/h4-8,11-12,20-21,24-25H,3,9-10,13H2,1-2H3,(H,22,23)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Agonist activity at recombinant human beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cyclic AMP after 30 mins				J Med Chem 60: 3252-3265 (2017) Article DOI: 10.1021/acs.jmedchem.6b01197 BindingDB Entry DOI: 10.7270/Q2M61NQX
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50108099 (CHEMBL3601204) Show SMILES CCc1n[nH]c2cc(OCCNC[C@H](O)c3cccc(NS(C)(=O)=O)c3)ccc12 |r| Show InChI InChI=1S/C20H26N4O4S/c1-3-18-17-8-7-16(12-19(17)23-22-18)28-10-9-21-13-20(25)14-5-4-6-15(11-14)24-29(2,26)27/h4-8,11-12,20-21,24-25H,3,9-10,13H2,1-2H3,(H,22,23)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	857	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Agonist activity at human alpha1A-adrenergic receptor expressed in HEK293 cells assessed as calcium flux by fluorescence assay				J Med Chem 58: 6048-57 (2015) BindingDB Entry DOI: 10.7270/Q2NG4SDR
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50108099 (CHEMBL3601204) Show SMILES CCc1n[nH]c2cc(OCCNC[C@H](O)c3cccc(NS(C)(=O)=O)c3)ccc12 |r| Show InChI InChI=1S/C20H26N4O4S/c1-3-18-17-8-7-16(12-19(17)23-22-18)28-10-9-21-13-20(25)14-5-4-6-15(11-14)24-29(2,26)27/h4-8,11-12,20-21,24-25H,3,9-10,13H2,1-2H3,(H,22,23)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	857	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Agonist activity at recombinant human alpha1A adrenergic receptor expressed in HEK293 cells assessed as intercellular Ca mobilization by Fura-2AM dye...				J Med Chem 60: 3252-3265 (2017) Article DOI: 10.1021/acs.jmedchem.6b01197 BindingDB Entry DOI: 10.7270/Q2M61NQX
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50108099 (CHEMBL3601204) Show SMILES CCc1n[nH]c2cc(OCCNC[C@H](O)c3cccc(NS(C)(=O)=O)c3)ccc12 |r| Show InChI InChI=1S/C20H26N4O4S/c1-3-18-17-8-7-16(12-19(17)23-22-18)28-10-9-21-13-20(25)14-5-4-6-15(11-14)24-29(2,26)27/h4-8,11-12,20-21,24-25H,3,9-10,13H2,1-2H3,(H,22,23)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Agonist activity at human beta2-adrenergic receptor expressed in CHO cells assessed as increase of cAMP level after 30 mins				J Med Chem 58: 6048-57 (2015) BindingDB Entry DOI: 10.7270/Q2NG4SDR
					More data for this Ligand-Target Pair