null

SMILES: ON(C=O)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=ANRXCWSBJHOAED-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50108139 (CHEMBL74365 | N-Hydroxy-N-[2-[4-(4-trifluoromethox...) Show SMILES ON(C=O)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H17F6NO6S/c24-22(25,26)16-3-1-15(2-4-16)21(30(32)14-31)13-37(33,34)20-11-9-18(10-12-20)35-17-5-7-19(8-6-17)36-23(27,28)29/h1-12,14,21,32H,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assay				J Med Chem 45: 219-32 (2001) BindingDB Entry DOI: 10.7270/Q2XP747B
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50108139 (CHEMBL74365 | N-Hydroxy-N-[2-[4-(4-trifluoromethox...) Show SMILES ON(C=O)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H17F6NO6S/c24-22(25,26)16-3-1-15(2-4-16)21(30(32)14-31)13-37(33,34)20-11-9-18(10-12-20)35-17-5-7-19(8-6-17)36-23(27,28)29/h1-12,14,21,32H,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of MMP9				ACS Med Chem Lett 2: 455-460 (2011) Article DOI: 10.1021/ml200031m BindingDB Entry DOI: 10.7270/Q2HQ40ZK
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50108139 (CHEMBL74365 | N-Hydroxy-N-[2-[4-(4-trifluoromethox...) Show SMILES ON(C=O)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H17F6NO6S/c24-22(25,26)16-3-1-15(2-4-16)21(30(32)14-31)13-37(33,34)20-11-9-18(10-12-20)35-17-5-7-19(8-6-17)36-23(27,28)29/h1-12,14,21,32H,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assay				J Med Chem 45: 219-32 (2001) BindingDB Entry DOI: 10.7270/Q2XP747B
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50108139 (CHEMBL74365 | N-Hydroxy-N-[2-[4-(4-trifluoromethox...) Show SMILES ON(C=O)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H17F6NO6S/c24-22(25,26)16-3-1-15(2-4-16)21(30(32)14-31)13-37(33,34)20-11-9-18(10-12-20)35-17-5-7-19(8-6-17)36-23(27,28)29/h1-12,14,21,32H,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assay				J Med Chem 45: 219-32 (2001) BindingDB Entry DOI: 10.7270/Q2XP747B
					More data for this Ligand-Target Pair