BDBM50108191 3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22367

SMILES: COc1ccccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1

InChI Key: InChIKey=BOZMVLDNYMRJIR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRB (Homo sapiens (Human))	BDBM50108191 (3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...) Show SMILES COc1ccccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C26H23N3O7S/c1-29-13-18(17-9-7-16(25(27)30)11-19(17)29)24(15-8-10-20-22(12-15)36-14-35-20)26(31)28-37(32,33)23-6-4-3-5-21(23)34-2/h3-13,24H,14H2,1-2H3,(H2,27,30)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.				Bioorg Med Chem Lett 12: 125-8 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KG6
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50108191 (3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...) Show SMILES COc1ccccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C26H23N3O7S/c1-29-13-18(17-9-7-16(25(27)30)11-19(17)29)24(15-8-10-20-22(12-15)36-14-35-20)26(31)28-37(32,33)23-6-4-3-5-21(23)34-2/h3-13,24H,14H2,1-2H3,(H2,27,30)(H,28,31)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptor				Bioorg Med Chem Lett 12: 125-8 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KG6
					More data for this Ligand-Target Pair