BDBM50108888 CHEMBL3596609

SMILES: NC(=O)c1ccc(Cl)c(c1)-c1ccc2N(CCCCc2c1)C(=O)c1c(F)cccc1Cl

InChI Key: InChIKey=FURKUIQVJAXHAH-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50108888 (CHEMBL3596609) Show SMILES NC(=O)c1ccc(Cl)c(c1)-c1ccc2N(CCCCc2c1)C(=O)c1c(F)cccc1Cl Show InChI InChI=1S/C24H19Cl2FN2O2/c25-18-9-7-16(23(28)30)13-17(18)14-8-10-21-15(12-14)4-1-2-11-29(21)24(31)22-19(26)5-3-6-20(22)27/h3,5-10,12-13H,1-2,4,11H2,(H2,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50108888 (CHEMBL3596609) Show SMILES NC(=O)c1ccc(Cl)c(c1)-c1ccc2N(CCCCc2c1)C(=O)c1c(F)cccc1Cl Show InChI InChI=1S/C24H19Cl2FN2O2/c25-18-9-7-16(23(28)30)13-17(18)14-8-10-21-15(12-14)4-1-2-11-29(21)24(31)22-19(26)5-3-6-20(22)27/h3,5-10,12-13H,1-2,4,11H2,(H2,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at Gal4 DNA binding domain-tagged human RORgammat expressed in HEK293T cells assessed as effect on receptor-mediated transcr...				Bioorg Med Chem Lett 25: 2991-7 (2015) BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair