BDBM50108890 CHEMBL3596612

SMILES: CC1(C)CCN(C(=O)c2c(F)cccc2Cl)c2ccc(cc12)-c1cc(ccc1Cl)C(N)=O

InChI Key: InChIKey=NZBXODFWVBTRFJ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50108890 (CHEMBL3596612) Show SMILES CC1(C)CCN(C(=O)c2c(F)cccc2Cl)c2ccc(cc12)-c1cc(ccc1Cl)C(N)=O Show InChI InChI=1S/C25H21Cl2FN2O2/c1-25(2)10-11-30(24(32)22-19(27)4-3-5-20(22)28)21-9-7-14(13-17(21)25)16-12-15(23(29)31)6-8-18(16)26/h3-9,12-13H,10-11H2,1-2H3,(H2,29,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50108890 (CHEMBL3596612) Show SMILES CC1(C)CCN(C(=O)c2c(F)cccc2Cl)c2ccc(cc12)-c1cc(ccc1Cl)C(N)=O Show InChI InChI=1S/C25H21Cl2FN2O2/c1-25(2)10-11-30(24(32)22-19(27)4-3-5-20(22)28)21-9-7-14(13-17(21)25)16-12-15(23(29)31)6-8-18(16)26/h3-9,12-13H,10-11H2,1-2H3,(H2,29,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at Gal4 DNA binding domain-tagged human RORgammat expressed in HEK293T cells assessed as effect on receptor-mediated transcr...				Bioorg Med Chem Lett 25: 2991-7 (2015) BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair