BDBM50108892 CHEMBL3596620

SMILES: CN(C(=O)c1c(F)cccc1Cl)c1ccc(cc1Br)-c1cc(ccc1Cl)C(N)=O

InChI Key: InChIKey=BWCMYRXRIIITLP-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50108892 (CHEMBL3596620) Show SMILES CN(C(=O)c1c(F)cccc1Cl)c1ccc(cc1Br)-c1cc(ccc1Cl)C(N)=O Show InChI InChI=1S/C21H14BrCl2FN2O2/c1-27(21(29)19-16(24)3-2-4-17(19)25)18-8-6-11(10-14(18)22)13-9-12(20(26)28)5-7-15(13)23/h2-10H,1H3,(H2,26,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50108892 (CHEMBL3596620) Show SMILES CN(C(=O)c1c(F)cccc1Cl)c1ccc(cc1Br)-c1cc(ccc1Cl)C(N)=O Show InChI InChI=1S/C21H14BrCl2FN2O2/c1-27(21(29)19-16(24)3-2-4-17(19)25)18-8-6-11(10-14(18)22)13-9-12(20(26)28)5-7-15(13)23/h2-10H,1H3,(H2,26,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	772	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at Gal4 DNA binding domain-tagged human RORgammat expressed in HEK293T cells assessed as effect on receptor-mediated transcr...				Bioorg Med Chem Lett 25: 2991-7 (2015) BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair