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SMILES: CN(C(=O)c1c(F)cccc1Cl)c1ccc(cc1C)-c1cc(ccc1Cl)C(N)=O

InChI Key: InChIKey=GHPAQSNKBOKFME-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108905   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50108905
PNG
(CHEMBL3596621)
Show SMILES CN(C(=O)c1c(F)cccc1Cl)c1ccc(cc1C)-c1cc(ccc1Cl)C(N)=O
Show InChI InChI=1S/C22H17Cl2FN2O2/c1-12-10-13(15-11-14(21(26)28)6-8-16(15)23)7-9-19(12)27(2)22(29)20-17(24)4-3-5-18(20)25/h3-11H,1-2H3,(H2,26,28)
PDB

UniProtKB/SwissProt

antibodypedia
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UniChem

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PubMed
n/an/a 4.22E+3n/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...

Bioorg Med Chem Lett 25: 2991-7 (2015)


BindingDB Entry DOI: 10.7270/Q2ZP47XQ
More data for this
Ligand-Target Pair