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BDBM50108911 CHEMBL3596594

SMILES: COc1ccc(cc1-c1ccc2N(CCCc2c1)C(=O)c1c(F)cccc1Cl)C(N)=O

InChI Key: InChIKey=CNQARGNTGJZZIE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108911   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))		BDBM50108911
PNG
(CHEMBL3596594)
Show SMILES COc1ccc(cc1-c1ccc2N(CCCc2c1)C(=O)c1c(F)cccc1Cl)C(N)=O
Show InChI InChI=1S/C24H20ClFN2O3/c1-31-21-10-8-16(23(27)29)13-17(21)14-7-9-20-15(12-14)4-3-11-28(20)24(30)22-18(25)5-2-6-19(22)26/h2,5-10,12-13H,3-4,11H2,1H3,(H2,27,29)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...

Bioorg Med Chem Lett 25: 2991-7 (2015)


BindingDB Entry DOI: 10.7270/Q2ZP47XQ
More data for this
Ligand-Target Pair